Allometric scaling in-vitro

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Allometric scaling in-vitro

About two decades ago, West and coworkers established a model which predicts that metabolic rate follows a three quarter power relationship with the mass of an organism, based on the premise that tissues are supplied nutrients through a fractal distribution network. Quarter power scaling is widely considered a universal law of biology and it is generally accepted that were in-vitro cultures to ...

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The design of living beings is not only a matter of molecular biology but also of geometry and physics. This was once more demonstrated with a biophysical model by G. B. West et al. (1) that had been fine-tuned to predict the famous scaling law of metabolism (2), namely a 3/4 power relation between body mass and energy consumption. While properties and predictions of the model are remarkable, a...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2017

ISSN: 2045-2322

DOI: 10.1038/srep42113